Fig. 1: PARK2 is downregulated in osteosarcoma tissues and cell lines, and PARK2 overexpression models are constructed. | Cell Death & Disease

Fig. 1: PARK2 is downregulated in osteosarcoma tissues and cell lines, and PARK2 overexpression models are constructed.

From: PARK2 inhibits osteosarcoma cell growth through the JAK2/STAT3/VEGF signaling pathway

Fig. 1

There are two representative cases comparing OS tissues and adjacent non-tumor tissues detected by immunohistochemistry (a). The expression of PARK2 mRNA in SAOS2, HOS, U2OS, and hFOB1.19 cells (b). The expression level of the protein Parkin was significantly enhanced in HOS and U2OS cell lines after transfection was detected using western blot assays (c) and immunofluorescence assays (d). Magnification, ×200 (a), ×1000 (d). Scale bar, 50 μm (a, d). **P < 0.01, ***P < 0.001

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