Fig. 2: Overexpression of PARK2 inhibits osteosarcoma cell proliferation in vitro.
From: PARK2 inhibits osteosarcoma cell growth through the JAK2/STAT3/VEGF signaling pathway
PARK2 significantly inhibits cell proliferation (a) and colony formation (b) compared with NC in HOS and U2OS cell lines. Compared with NC, PARK2 downregulated the cell proliferation rate (c) and arrested the progression of the cell cycle (d) in HOS and U2OS cell lines. These data were detected by an immunofluorescence assay and flow cytometry, respectively. Magnification, ×400 (c). Scale bar, 50 μm (c). *P < 0.05, **P < 0.01.Each assay was repeated three times
