Fig. 6: Overexpression of PARK2 inhibits osteosarcoma cell tube formation in vitro.
From: PARK2 inhibits osteosarcoma cell growth through the JAK2/STAT3/VEGF signaling pathway
NC was used as the control group. The formation of capillary-like structures was obviously suppressed by PARK2. The co-culture with IL-6 (25 ng/ml) or stattic (10 μM) was also evaluated (a). The western blot analysis of the expression of the proteins p-Jak2, p-STAT3, STAT3, and VEGF post co-culture with IL-6 (25 ng/ml, 30 min) or stattic (10 μM, 2 h) (b). Magnification, ×100 (a). Scale bar, 200 μm (a). *P < 0.05, **P < 0.01, ***P < 0.001. Each assay was repeated three times
