Fig. 2: CISD2 and its role in MAMs. | Cell Death & Disease

Fig. 2: CISD2 and its role in MAMs.

From: Wolfram syndrome: MAMs’ connection?

Fig. 2

CISD2 is expressed in the ER membrane and in the outer mitochondrial membranes. The protein resides in the MAMs where it could oligomerize. CISD2 interacts with BCL2 to regulate Ca2+ homeostasis and apoptosis. Finally, CISD2 interacts with Gimap5 to control the differentiation of adipocytes

Back to article page