Table 1 Rbf/f;Bax+/−;α-Cre males and Rbf/f;Bax−/− females breeding offspring

From: Rb is required for retinal angiogenesis and lamination

Alleles

Predicted frequency

Observed frequency

Rb f/f

100%

96/96 (100%)

α-Cre

50%

50/96 (52%)

Bax −/−

50%

48/96 (50%)

Bax −/− ;α-Cre

25%

5/96 (5.2%)

  1. Rb retinoblastoma tumor suppressor, f/f floxed, α-Cre Pax6 alpha enhancer Cre
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