Fig. 7: TRIP13 mediates EMT by interacting with YWHAZ.
From: TRIP13 promotes tumor growth and is associated with poor prognosis in colorectal cancer
a Western blotting of EMT markers, TRIP13 and YWHAZ were performed in TRIP13 overexpressing CRC cells which transfected with siRNAs targeting YWHAZ, to determine whether TRIP13 mediates EMT in a YWHAZ dependent way. b, c The effect of knockdown of YWHAZ in TRIP13 overexpressing CRC cells on migration (b), and invasion (c). d YWHAZ IHC scores of the staining intensity level in representative tumor tissues. The bars are as indicated. e Spearman correlation coefficient plots for TRIP13 and YWHAZ. r = 0.532, 95%CI: (0.421–0.627), p < 0.001
