Fig. 1: LASP1 expression is upregulated in metastatic NPC and associated with tumor progression and poor prognosis. | Cell Death & Disease

Fig. 1: LASP1 expression is upregulated in metastatic NPC and associated with tumor progression and poor prognosis.

From: LASP1 promotes nasopharyngeal carcinoma progression through negatively regulation of the tumor suppressor PTEN

Fig. 1

a LASP1 expression assessed by real-time PCR in eight NPC cell lines and the normal epithelial cell line NP69. Date are means ± SD of three independent experiments (*P < 0.05, **P < 0.01, ***P < 0.001). b Western blot analysis for the expression of LASP1 in eight NPC cell lines and the normal epithelial cell line NP69. Immunosignal values were quantified by Gel-Pro analyzer. LASP1 expression in the individual cells was calculate as LASP1 expression relative to β-actin. Date are means ± SD of three independent experiments (*P < 0.05, **P < 0.01, ***P < 0.001). c Representative IHC analysis of LASP1 protein expression in normal nasopharyngeal squamous epitheliums, non-metastatic NPC (nm NPC), and metastatic NCP (mNPC) tissues. d Graphical illustration of statistical LASP1 expression distribution in 60 cases of normal tissues and 210 cases of NPC tissues. e Kaplan–Meier survival curves for CRC patients with distinct expression levels of LASP1

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