Fig. 1: HeLa-XR is a radioresistant cervical cancer cell line.
From: GADD45α sensitizes cervical cancer cells to radiotherapy via increasing cytoplasmic APE1 level
a HeLa-XR cells showed higher survival fraction compared to HeLa cells when treated with the same radiation dose. Indicated cells were treated with indicated doses of radiation followed by clonogenic assay. b Comet assay showing that HeLa-XR cells were not sensitive to radiation-induced DNA damage compared to HeLa cells. c HeLa-XR cells showed reduced apoptotic cell population compared to HeLa cells when treated with 6 Gy radiation. d HeLa-XR cells showed resistance to radiation-induced G2/M cell cycle arrest compare to HeLa cells. Each experiment was repeated three times. **p < 0.01; ***p < 0.001. NS no significance
