Fig. 5: PIWIL2 enhances formation of CK2α-HDAC3 complex to phosphorylate HDAC3. | Cell Death & Disease

Fig. 5: PIWIL2 enhances formation of CK2α-HDAC3 complex to phosphorylate HDAC3.

From: PIWIL2 suppresses Siah2-mediated degradation of HDAC3 and facilitates CK2α-mediated HDAC3 phosphorylation

Fig. 5

a Co-immunoprecipitation assays showed the interaction of PIWIL2, CK2α, and HDAC3. b Cell lysates were immunoprecipitated with anti-HA antibody, and then a secondary immunoprecipitation assay was performed with anti-PIWIL2 antibody. c Immunofluorescence assays showed the co-localization of PIWIL2, CK2α, and HDAC3. d, e PIWIL2 facilitates CK2α binding with HDAC3 to phosphorylate HDAC3

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