Fig. 1: P + M induces progressive dopaminergic neurodegeneration and α-synuclein aggregation. | Cell Death & Disease

Fig. 1: P + M induces progressive dopaminergic neurodegeneration and α-synuclein aggregation.

From: Taurine protects dopaminergic neurons in a mouse Parkinson’s disease model through inhibition of microglial M1 polarization

Fig. 1

a Mice were treated with P + M. After 2, 4 and 6 weeks of initial treatment, dopaminergic neurons were immunostained with anti-TH antibody and the representative images were shown. b The number of TH+ neurons in the SNpc was quantified. c After 6 weeks of treatment, the expression of α-synuclein in midbrain was detected by using western blot and the representative blots were shown. GAPDH was used as an internal control. d The band density of blots was quantified. *p< 0.05, **p < 0.01; Scale bar = 200 μm

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