Fig. 5: Impaired EGFR signaling pathway in ZBTB20-deficient hepatocytes can be corrected by EGFR overexpression. | Cell Death & Disease

Fig. 5: Impaired EGFR signaling pathway in ZBTB20-deficient hepatocytes can be corrected by EGFR overexpression.

From: ZBTB20 regulates EGFR expression and hepatocyte proliferation in mouse liver regeneration

Fig. 5

a Primary hepatocytes from LZB20KO and control mice were stimulated with EGF (1 ng/ml) for indicated times following 12 h of serum starvation, and the expression and phosphorylation of EGFR, ERK, and AKT were analyzed by western blot. b Hepatocytes were infected with adenoviruses Ad-EGFR or Ad-GFP (MOI = 10) at 24 h prior to 12 h of serum starvation, and followed by EGF stimulation for 5 min. The expression and phosphorylation of EGFR, ERK, and AKT were analyzed by western blot

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