Fig. 3: In vivo basophil counts in human low and high serum IgE donors and mice that are sufficient or deficient for FcεRI. | Cell Death & Disease

Fig. 3: In vivo basophil counts in human low and high serum IgE donors and mice that are sufficient or deficient for FcεRI.

From: IL-3 but not monomeric IgE regulates FcεRI levels and cell survival in primary human basophils

Fig. 3

Comparison of basophil cell counts in blood from low ( ≤ 32 kU/L, n = 6, gray bars) versus high ( > 32 kU/L, n = 9, black bars) serum IgE donors a. b Correlation between blood basophil cell counts and total serum IgE in different blood donors (n = 15). c Representative flow cytometry measurement of CD49+/ CD200R3+ blood basophils in wildtype, huFcεRIαtg and huFcεRIα−/− mice. d Isotype staining control for CD49b. e Absolute quantification of blood basophil cell counts in wildtype (n = 6), huFcεRIαtg (n = 4), and huFcεRIα−/− (n = 8) mice. Data are shown as mean values ± SEM

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