Fig. 5: Knockdown of RXR rebuilt adult cell’s capacity for migration and blood vessel formation, which was enhanced by ER overexpression.

a, b Determination of cell migration by wound healing in hMSCs and HUVECs overexpressing RXRα. c The migration of HUVECs with siRXRα knockdown or/and ERα overexpression. d Blood vessel formation determined by Matrigel assay in HUVECs with siRXRα knockdown or/and ERα overexpression (24 h culture in Matrigel)