Table 2 Univariate and multivariate survival analysis of overall survival in 73 patients with CRC

From: HMGB1 released by irradiated tumor cells promotes living tumor cell proliferation via paracrine effect

Variables

Univariate analysis

Multivariate analysis

p-value

p-value

RR

95%CI

HMGB1 expression

(low vs high)

0.003

0.011

0.230

0.074–0.710

Age

(<61 vs ≥61)

0.445

0.482

0.751

0.337–1.672

Gender

(male vs female)

0.886

0.445

1.336

0.635–2.809

Grade

(I vs II–III)

0.018

0.047

0.396

0.158–0.988

TNM stage

(I–II vs III–IV)

0.001

0.469

2.629

0.192–36.088

Lymph nodes

(negative vs positive)

0.001

0.071

0.098

0.008–1.219

Metastasis

(negative vs positive)

0.017

0.144

0.362

0.093–1.416