Fig. 5: FOXM1 was overexpressed in the docetaxel-resistant cancer cells, which contributed to the maintenance of the CSC phenotype. | Cell Death & Disease

Fig. 5: FOXM1 was overexpressed in the docetaxel-resistant cancer cells, which contributed to the maintenance of the CSC phenotype.

From: FOXM1 contributes to taxane resistance by regulating UHRF1-controlled cancer cell stemness

Fig. 5

a The protein levels of FOXM1 were analyzed in CNE2 and CNE2TR cells, DU145 and DU145-DR cells, and SKOV3 and SKOV3R cells by Western blot. b FOXM1 depletion decreased the expression of CSC-associated molecules ALDH1, NANOG, SOX2 and SHH in CNE2TR, and DU145-DR cells. c The ectopic overexpression of FOXM1 in DU145 or CNE2 cells elevated the expression levels of CSC-associated molecules ALDH1, NANOG, SOX2, and SHH

Back to article page