Table.1 The effects of SIPS and rhG-CSF on bodyweight and organ indexes

From: Sarcodon imbricatus polysaccharides improve mouse hematopoietic function after cyclophosphamide-induced damage via G-CSF mediated JAK2/STAT3 pathway

 

Days

CTRL

CTX (100 mg/kg)

SIPS (50 mg/kg)

   

--

rhG-CSF (22.5 μg/kg)

SIPS (25 mg/kg)

SIPS (50 mg/kg)

SIPS (100 mg/kg)

 

Body weight (g)

1st day

24.9±2.1

24.1±1.2

24.1±1.6

25.2±1.7

24.5±0.8

24.8±1.9

25.2±1.8

4th day

26.9±1.4

19.9±1.3###

19.5±1.5

20.8±1.9

19.9±1.7

20.2±1.9

26.3±2.4

11th day

28.7±1.3

20.1±2.2###

22.8±1.6*

22.8±1.7*

22.1±1.3*

21.8±2.1*

27.3±2.5

18th day

29.6±1.6

18.5±3.3###

22.6±1.4**

21.2±2.4*

21.8±2.1*

21.8±2.1*

28.6±1.2

28th day

30.5±1.6

19.1±1.4###

23.8±1.1**

21.9±2.3*

23.5±2.5**

22.8±1.8*

29.6±2.4

Organ index (%)

Spleen index

4.1±0.7

12.3±3.8###

11.5±1.8

10.7±3.0

10.5±2.2*

9.9±2.5*

4.2±0.6

Thymus index

1.9±0.3

1.2±0.4###

1.9±0.5**

1.8±0.4*

1.9±0.6**

1.7±0.3*

1.8±0.3

Liver index

53.2±5.6

62.7±7.1###

59.4±3.8

60.4±4.4

58.9±3.2*

60.3±3.8

52.8±4.1

Kidney index

15.6±1.2

16.1±1.0

16.7±0.9

16.2±1.1

16.5±1.2

16.2±1.1

16.1±1.0

  1. Data are expressed as mean ± S.D. (n = 10/group)
  2. CTX cyclophosphamide, rhG-CSF recombinant human granulocyte colony-stimulating factor, SIPS Sarcodon imbricatus polysaccharides
  3. ###P < 0.001 vs. control group, *P < 0.01 and **P < 0.01 vs. model group
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