Fig. 4: Apoptosis-related genes were affected in OX40-deficient cDNT under IL-2 stimulation. | Cell Death & Disease

Fig. 4: Apoptosis-related genes were affected in OX40-deficient cDNT under IL-2 stimulation.

From: Critical role of OX40 in the expansion and survival of CD4 T-cell-derived double-negative T cells

Fig. 4

a Relative mRNA expression of anti-apoptosis genes Bcl-2 (a), Bcl-xl (b), and Survivin (c), and pro-apoptosis genes Bcl2l11 (d) in B6 cDNT and OX40 KO cDNT stimulated with IL-2 or without IL-2 at different time points. Relative changes of the genes in the presence or absence of IL-2 in B6 cDNT compared with that in OX40 KO cDNT. The data are presented as the mean ± SD, n = 5 in each group. *p < 0.05, **p < 0.01, NS no significance

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