Fig. 4: Effects of prenatal ethanol exposure (PEE, 4  g/kg per day) on the serum corticosterone (CORT) concentration and potential hypothalamic excitatory ability in male foetal rats. | Cell Death & Disease

Fig. 4: Effects of prenatal ethanol exposure (PEE, 4  g/kg per day) on the serum corticosterone (CORT) concentration and potential hypothalamic excitatory ability in male foetal rats.

From: Programming for increased expression of hippocampal GAD67 mediated the hypersensitivity of the hypothalamic–pituitary–adrenal axis in male offspring rats with prenatal ethanol exposure

Fig. 4

a Serum CORT concentration. b–k Hypothalamic expression of corticotrophin-releasing hormone (CRH), arginine vasopressin (AVP), paired box 6 (Pax6), T-box brain protein 2 (Tbr2), vesicular glutamate transporter 2 (VGluT2), post-synaptic density 95 (PSD95), Ca2+/calmodulin-dependent protein kinase II-α (α-CaMKII), mammalian achaete-scute homologue-1 (Mash1), glutamic acid decarboxylase 65 (GAD65) and Reelin. l Hypothalamic expression ratio of VGluT2/GAD65. Mean ± S.E.M., n = 8 litters. *P < 0.05, *P < 0.01 vs. control

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