Fig. 5: STX2 activated the NF-κB signaling pathway by interacting with TRAF6. | Cell Death & Disease

Fig. 5: STX2 activated the NF-κB signaling pathway by interacting with TRAF6.

From: STX2 promotes colorectal cancer metastasis through a positive feedback loop that activates the NF-κB pathway

Fig. 5

a, b The interaction between STX2 and TRAF6 in CRC cells was determined by Co-IP analysis. c The co-localization of STX2 and TRAF6 in CRC cells by IF. d IHC analysis of STX2 and TRAF6 protein expression in the same CRC samples. e The mRNA expression levels of STX2 and TRAF6 were measured by real-time PCR (2−ΔCт). f Spearman correlation analysis of STX2 and TRAF6 mRNA expression. g–i Correlation analysis between STX2 and TRAF6, MMP9, and VEGF-C mRNA expression in GSE17538

Back to article page