Table 1 CI values of vorinostat and QC in Jurkat cells

From: Vorinostat and quinacrine have synergistic effects in T-cell acute lymphoblastic leukemia through reactive oxygen species increase and mitophagy inhibition

Dose vorinostat (μM)

Dose QC (μM)

Combination index

2

5

0.61736

2

2.5

0.32931

2

1.25

0.31165

1

5

0.63397

1

2.5

0.37588

1

1.25

0.33006

0.5

5

0.60765

0.5

2.5

0.40593

0.5

1.25

0.30434

0.25

5

0.67347

0.25

2.5

0.43356

0.25

1.25

0.38574