Table 4 CI values of panobinostat and QC in Molt-4 cells

From: Vorinostat and quinacrine have synergistic effects in T-cell acute lymphoblastic leukemia through reactive oxygen species increase and mitophagy inhibition

Dose panobinostat (nM)

Dose QC (μM)

Combination index

20.0

10

2.06834

20.0

5

0.98944

20.0

2.5

0.91221

20.0

1.25

0.88823

10.0

10

1.15378

10.0

5

0.65907

10.0

2.5

0.68349

10.0

1.25

0.64859

5.0

10

0.71968

5.0

5

0.52512

5.0

2.5

0.48863

5.0

1.25

0.57159

2.5

10

1.47339

2.5

5

0.44161

2.5

2.5

0.36865

2.5

1.25

2.05957

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