Fig. 2: miR-129 was an upstream regulator for IGF-1. | Cell Death & Disease

Fig. 2: miR-129 was an upstream regulator for IGF-1.

From: miR-129 controls axonal regeneration via regulating insulin-like growth factor-1 in peripheral nerve injury

Fig. 2

a Sketches of the construction of wild-type or mutant IGF-1 3′-UTR reporter plasmid for miR-129. b The relative luciferase activity was analyzed after the wild-type or mutant IGF-1 3′-UTR reporter plasmid co-transfected into HEK 293T cells with miR-129 mimic (miR-129) or mimic control (NC). **p < 0.01 versus control. Expression of miR-129 in DRGs (c) and proximal nerve stumps (d) following sciatic nerve transection. * p < 0.05 and ** p < 0.01 versus control (0 h post nerve injury). U6 served as internal reference

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