Fig. 8
From: Consequences of blunting the mevalonate pathway in cancer identified by a pluri-omics approach
Central carbon metabolism in cancer. Metabolite and gene expression changes in response to (lovastatin + docetaxel) treatment for 36 h. The metabolomics and lipidomics signaling pathways were overlaid with the alterations in gene expression following (lovastatin + docetaxel) treatment compared to control cells after 36 h. The color code was as follows: blue boxes and blue circles referred to down-regulated genes and down-regulated metabolites, respectively. Red boxes and red circles referred to up-regulated genes and up-regulated metabolites, respectively
