Table 1 Evolution of the 111 metabolites identified in the (lovastatin + docetaxel) vs. control condition after 36 h of treatment

2,3-Dihydroxypropyl palmitate

Cis-4-hydroxy-d-proline

L-Glutamine

Phosphoric acid

Choline

2-Hydroxy-3-Methylbutyric acid

Citric acid

L-Homoserine

Propionyl-L-carnitine

Fumarate

2-Oxovaleric acid

Creatine

L-Isoleucine

Pyridoxal

L-Glutathion

3-Hydroxytyramine

Creatinine

L-Leucine

Pyridoxine

L-Tryptophan

3-Methyl-2-oxobutanoic acid

Cyclohexene-3,5-dione

L-Lysine

Pyroglutamic acid

Pantothenic acid

4-Methyl-2-oxovaleric acid

Cystathionine

L-Methionine

Pyrophosphate

Spermidine

5-Aminovaleric acid

Dehydroabietic acid

L-Phenylalanine

Ribothymidine

Threonine

5-Deoxy-5-methylthioadenosine

D-Fructose

L-Proline

Sarcosine

SM 16:0

5-Methylcytidine

D-Glucose

L-Tyrosine

Stearoylglycerol

SM 18:0

Acetate

Dihydrouracil

Maleic acid

Succinate

SM 20:0

Adenosine

D-Ribose

Methylmalonic acid

Talose

SM 22:0

Adipic acid

Formamide

Monopalmitoylglycerol

Taurine

SM 24:0

Alpha-hydroxyisobutyric acid

Fructose di-phosphate

Myo-inositol

TG (52:2)

SM 18:1

Alpha-ketoglutaric acid

Glutamate

Myristic acid

TG (52:3)

SM 20:1

Aminoadipic acid

Glyceraldehyde

N-acetyl-asp-Glu

TG (54:2)

SM 22:1

Aminomalonic acid

Glycerol stearate

N-acetyl-d-glucosamine

Tryptophan

SM 24:1

Arginine

Glycerylphosphorylcholine

N-acetyl-l-aspartate

Tyramine

PC (28:0)

Asparagine

Hexadecanoic acid

N-acetyl-l-glutamate

Uric acid

PC (30:1)

Aspartate

Hippuric acid

Nicotinamide

Uridine

PC (32:2)

Azelaic acid

Hydroxybutyric acid

O-acetyl carnitine

Uridine-5′-monophosphate

PC (34:3)

Beta-Alanine

Hypotaurine

Ornithine

Valine

PC (34:5)

Betaine

Lactic acid

O-succinyl-l-homoserine

Cer(d18:1/16:0)

L-Alanine

Phosphoglyceric acid