Fig. 5: Δ133p53α increases hTERT mRNA levels and telomerase activity. | Cell Death & Disease

Fig. 5: Δ133p53α increases hTERT mRNA levels and telomerase activity.

From: Δ133p53α, a natural p53 isoform, contributes to conditional reprogramming and long-term proliferation of primary epithelial cells

Fig. 5

a qRT-PCR analysis of hTERT mRNA levels in Δ133p53α-overexpressing (Δ133p53α-OE) HFK and HPEC cells three passages after selection in KGM. The empty GFP-tagged vector was used as a control. β2-microglobulin mRNA was used for normalization. Data are mean ± S.D. from three independent experiments. **P < 0.01; ***P < 0.001. b Telomerase activity was measured in the same Δ133p53α-OE HFK and HPEC cells three passages after selection in KGM. The empty GFP-tagged vector was used as a control. Data are expressed as mean ± S.D. from three independent experiments. **P < 0.01

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