Fig. 3: Dose-depended efficacy study of annonacin on cancer and normal cell viability.

a MTT cytotoxicity assay in MCF-7, MCF12-F, Mia Paca-2, and SUM-159 cell lines treated with Graviola in a dose-dependent manner and cisplatin 10 μM, p < 0.001. b MTT cytotoxicity assay in MCF-7, MCF12-F, Mia Paca-2, and SUM-159 cell lines treated with Graviola extract, ouabain 1 mM, and DBHQ 5 μM, p < 0.001. c Caspase 3/7 Green Fluorescent kit on Mia-PACA-2 cell lines. Statistical analysis is determined by one-way ANOVA (p < 0.05)