Fig. 3: Immunoreactivity for GFAP and IBA-1 in striatum and substantia nigra pars compacta (SNc) of A53T and WT mice. | Cell Death & Disease

Fig. 3: Immunoreactivity for GFAP and IBA-1 in striatum and substantia nigra pars compacta (SNc) of A53T and WT mice.

From: NCX1 and NCX3 as potential factors contributing to neurodegeneration and neuroinflammation in the A53T transgenic mouse model of Parkinson’s Disease

Fig. 3

Representative sections and histograms of striatum and SNc immunostained for GFAP and IBA-1. The bar graphs report the number of GFAP-positive cells (green) in striatum (a) and SNc (b) of A53T mice, expressed as a percentage of WT mice. c The bar graphs report the number of IBA-1-positive cells (red) in striatum and d in SNc of 12-month-old A53T mice, expressed as a percentage of WT mice. N = 8 animals were used for each experimental group. *P < 0.05 vs respective WT mice. Scale bar: 50, 75, and 100 µm

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