Fig. 6: NCX expression and activity in midbrain neurons obtained from A53T mouse embryos. | Cell Death & Disease

Fig. 6: NCX expression and activity in midbrain neurons obtained from A53T mouse embryos.

From: NCX1 and NCX3 as potential factors contributing to neurodegeneration and neuroinflammation in the A53T transgenic mouse model of Parkinson’s Disease

Fig. 6

a Bar graphs report the mean ± S.E.M. of the densitometric values of NCX1 and NCX3 expression in primary midbrain A53T and WT neurons normalized to the respective α-Tubulin. *P < 0.05 vs respective WT neurons; b cytosolic and mitochondrial Ca2+ concentrations in midbrain neurons obtained from A53T and WT mouse embryos. Values were expressed as mean of the percentage ± S.E.M. *P < 0.05 vs WT neurons. Images are representative of X-Rod 1 (red) and Fluo-3 (green) distribution in cytosol and in mitochondria in WT and in A53T Transgenic neurons respectively. Scale bar: 100 μm

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