Fig. 1: SLC15A3 was preferentially expressed in macrophages and upregulated by TLR4 activation. | Cell Death & Disease

Fig. 1: SLC15A3 was preferentially expressed in macrophages and upregulated by TLR4 activation.

From: Regulation and biological role of the peptide/histidine transporter SLC15A3 in Toll-like receptor-mediated inflammatory responses in macrophage

Fig. 1

a The expression profile of Slc15a3 in mouse leukocytes based on cDNA data. b mRNA expression of Slc15a3 in mouse PBMCs, BMDCs, PMs and BMDMs isolated from ICR mice. c, d mRNA and protein expression of Slc15a3 in mouse PMs (c) and BMDMs (d) treated with 100 ng/mL LPS for specified periods of time. Quantification of protein (i.e., SLC15A3/GAPDH ratio) is shown in the right side of each Western blot figure. One-way ANOVA followed by Dunnett’s test was used to evaluate the statistical differences. *P < 0.05, **P < 0.01, and ***P < 0.001 compared with 0 h. The data are expressed as mean ± SE (n = 3)

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