Fig. 2: Karonudib has cytotoxic effect, irrespective of melanoma driver mutations. | Cell Death & Disease

Fig. 2: Karonudib has cytotoxic effect, irrespective of melanoma driver mutations.

From: A patient-derived xenograft pre-clinical trial reveals treatment responses and a resistance mechanism to karonudib in metastatic melanoma

Fig. 2

a Oncoprint showing melanoma hot-spot mutations found in three response groups. Transparent colors indicate low confidence variants (Materials and methods). b, c Volcano plots showing differentially expressed genes between the progression group and (b) suppression group, and (c) regression group

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