Fig. 4: TST suppressed survival pathways induced by BEZ235. | Cell Death & Disease

Fig. 4: TST suppressed survival pathways induced by BEZ235.

From: HDAC6 inhibitor TST strengthens the antiproliferative effects of PI3K/mTOR inhibitor BEZ235 in breast cancer cells via suppressing RTK activation

Fig. 4

a T47D and b BT474 cells were stimulated with BEZ235 and TST for 36 h. Total protein and their phosphorylation levels of RTKs were detected by western blot. c, d To further demonstrate the downstream signal changes, p-S6K, p-AKT, and acetylated-α-tubulin were also detected in both cell lines. e T47D and f BT474 cells were treated with BEZ235 and TST for 36 h, cellular lysates were applied to p-RTK arrays

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