Fig. 6: BEZ235 and TST displayed synergistic effect on cell cycle arrest. | Cell Death & Disease

Fig. 6: BEZ235 and TST displayed synergistic effect on cell cycle arrest.

From: HDAC6 inhibitor TST strengthens the antiproliferative effects of PI3K/mTOR inhibitor BEZ235 in breast cancer cells via suppressing RTK activation

Fig. 6

a T47D and b BT474 cells were treated with BEZ235 and TST for 36 h. Cells were then trypsinized, washed, and re-suspended in 1× binding buffer. Cell cycle distribution was studied by using flow cytometry following PI staining. c, d Data of cell cycle distribution were calculated. e T47D and f BT474 cells were treated with BEZ235 and TST for 36 h. Cell cycle-related proteins were detected by western blotting

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