Table 2 Histology details of KRAS-c.34G mutant adenomas

From: Circulating tumor DNA in patients with colorectal adenomas: assessment of detectability and genetic heterogeneity

Sample ID

No. of FFPE blocks

% Fractional abundance in FFPE samples

Histology

Polyp dimensions (mm)

H183

1

0.9667

Mid transverse (LG TA)

10 × 6

H314

1

2.7618

Distal sigmoid (LG TA)

16 × 7 × 5

H325

1

1.0923

Colonic (LG TVA)

20 × 14 × 8

H329

2

0.0006–5.3010

Rectal (LG VA)

11 × 9 × 9

14 × 9 × 7

H338

2

0.7336–3.5509

Sigmoid (LG TVA)

16 × 15 × 10

H344

2

0.0000–1.9799

Colonic (LG TVA)

20 × 20 × 10

H775

1

11.093

Colonic (MD AC, Duke’s C1)

N/A

H785

1

9.0330

Recto-sigmoid (sessile HG TVA, focal pT1 AC)

16 × 11 × 9

  1. Histology and polyp dimensions were obtained from the histology reports. For cases where more than one FFPE blocks were tested, lowest and highest mutation frequencies are reported
  2. LG low-grade, HG high-grade, TA tubular adenoma, VA villous adenoma, TVA tubulovillous adenoma, MD mild differentiated, AC adenocarcinoma
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