Table 3 Histology details of KRAS-c.38G mutant adenomas

From: Circulating tumor DNA in patients with colorectal adenomas: assessment of detectability and genetic heterogeneity

Sample ID

No. of FFPE blocks

% Fractional abundance in FFPE samples

Histology

Polyp dimensions (mm)

H142

1

16.3347

Sigmoid (LG TVA)

17 × 10 × 15

H149

8

0.0000–3.8205

Sigmoid (LG TVA)

15 × 15 × 15–25 × 20 × 25

H151

1

5.0351

Splenic flexure (LG TA)

5 × 4

H183

1

6.2698

Mid transverse(LG TA)

10 × 6

H190

1

30.4348

Recto-sigmoid (LG TVA)

14

H334

2

0.0000–4.6363

Recto-sigmoid (LG TA+TVA)

7 × 9 × 4–12 × 10 × 4

H335

2

0.0565–1.4967

Sigmoid-cecal (LG TVA)

10–12

H336

2

2.3732–7.1057

Sigmoid (LG TVA)

14

H347

2

0.0500–2.1894

Recto-sigmoid (LG TVA)

21 × 15 × 10

  1. For cases where more than one FFPE blocks were tested, lowest and highest mutation frequencies  are reported
  2. LG low-grade, HG high-grade, TA tubular adenoma, VA villous adenoma, TVA tubulovillous adenoma, MD mild differentiated, AC adenocarcinoma