Fig. 2 | Cell Death & Disease

Fig. 2

From: Protease-activated receptor 2 signaling modulates susceptibility of colonic epithelium to injury through stabilization of YAP in vivo

Fig. 2

Knockout of PAR2 reduced YAP protein in vivo. a Protein and (b) mRNA expression of YAP in mouse colon was detected with western blotting or RT-PCR, respectively. c Immunohistochemical analysis of paraffin-embedded colon sections from wild-type and PAR2 knock-out mice. Scale bars represent 100 μm. d Number of colon epithelial cell with nuclear YAP was quantified. Data are shown as mean ± SEM. N.S., no significance; ***p < 0.001 vs. corresponding control

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