Fig. 5: Effects of DHA-37 on A549 tumor xenografts. | Cell Death & Disease

Fig. 5: Effects of DHA-37 on A549 tumor xenografts.

From: Novel dihydroartemisinin derivative DHA-37 induces autophagic cell death through upregulation of HMGB1 in A549 cells

Fig. 5

Nude mice bearing an A549-derived tumor were treated with DHA-37 or 5-Fluorouracil (5-fu). a Body weights of mice were measured. b Tumor volumes were measured every day. c Mice were killed and tumors were then photographed and weighed. d Tumor lysates for western blot analyses by using indicated antibodies. e Immunofluorescence staining was performed to investigate HMGB1 expression in tumor tissues. The data are presented as the mean ± S.D. n = 8. *p < 0.05, **p < 0.01

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