Fig. 6: The expression of Bcl-xL was positively correlated with the PGAM5 expression level in HCC. | Cell Death & Disease

Fig. 6: The expression of Bcl-xL was positively correlated with the PGAM5 expression level in HCC.

From: High PGAM5 expression induces chemoresistance by enhancing Bcl-xL-mediated anti-apoptotic signaling and predicts poor prognosis in hepatocellular carcinoma patients

Fig. 6

a Representative immunohistochemistry images show higher expression Bcl-xL in samples with high PGAM5 levels and lower expression Bcl-xL in samples with low PGAM5 levels. Scale bars: 50 um. b Positively correlation between Bcl-xL and PGAM5 in HCC samples, which was determined with linear regression lines and Pearson correlation significance. (upper: the testing cohort, TMUCH; lower: the validation cohort, SYSUCC). c, d High expression of Bcl-xL is associated with poorer overall survival (left) and progression-free survival (right) in both the testing cohort (c) and the validation cohort (d)

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