Table 1.2 Predictive variables for OS and PFS of 212 patients with HCC by univariate survival analysis (SYSUCC)
Variable | OS (months) | PFS (months) | |||
|---|---|---|---|---|---|
Cases | HR(95% CI) | p value | HR(95% CI) | p value* | |
Age(years) | 0.627 | 0.668 | |||
≤47.9# | 105 | 1.0 | 1.0 | ||
>47.9 | 107 | 1.092 (0.77–1.542) | 1.061 (0.72–1.603) | ||
Gender | 0.045 | 0.058 | |||
Male | 174 | 1.651 (1.012–2.688) | 1.352 (0.083–2.125) | ||
Female | 38 | 1.0 | 1.0 | ||
Hepatitis history | 0.810 | 0.524 | |||
Yes | 164 | 1.053 (0.692–1.602) | 1.072 (0.059–1.633) | ||
No | 48 | 1.0 | 1.0 | ||
AFP(ng/ml) | 0.000 | 0.000 | |||
≤20 | 67 | 1.0 | 1.0 | ||
>20 | 145 | 2.262 (1.490–3.434) | 3.389 (2.157–4.886) | ||
Tumor size(cm) | 0.000 | 0.002 | |||
≤5 | 59 | 1.0 | 1.0 | ||
>5 | 153 | 6.295 (3.688–10.747) | 3.963 (2.597–5.559) | ||
Tumor multiplicity | 0.000 | 0.001 | |||
Single | 128 | 1.0 | 1.0 | ||
Multiple | 84 | 3.480 (2.429–4.987) | 3.669 (2.582–5.139) | ||
Stage | 0.000 | 0.000 | |||
I–II | 88 | 1.0 | 1.0 | ||
III–IV | 124 | 5.393 (3.525–8.252) | 4.847 (3.331–9.147) | ||
Vascular invasion | 0.000 | 0.000 | |||
Yes | 108 | 4.923 (3.331–7.322) | 4.336 (3.139–6.736) | ||
No | 104 | 1.0 | 1.0 | ||
PGAM5 expression | 0.016 | 0.003 | |||
Low | 100 | 1.0 | 1.0 | ||
High | 112 | 3.165 (2.785–6.133) | 4.391 (2.336–8.461) | ||
