Table 2.2 Multivariate Cox regression analysis for OS and PFS in patients with HCC (SYSUCC)

From: High PGAM5 expression induces chemoresistance by enhancing Bcl-xL-mediated anti-apoptotic signaling and predicts poor prognosis in hepatocellular carcinoma patients

Variable

OS

PFS

HR

95%Cl

p value

HR

95%Cl

p value

AFP, ng/ml (≤20 vs >20)

1.452

1.018–2.069

0.041

2.316

1.527–3.663

0.025

Tumor size, cm (≤5 vs >5)

1.621

0.888–3.053

0.165

1.337

0.726–2.176

0.216

Tumor multiplicity(single vs multiple)

1.736

0.969–42.112

0.064

2.225

1.362–3.681

0.026

Stage (I–II vs III–IV)

1.565

0.908–2.456

0.132

1.669

1.315–2.538

0.043

Vascular invasion

1.901

1.234–2.929

0.004

2.013

1.662–3.269

0.026

PGAM5 expression(positive vs negative)

1.862

1.307–3.882

0.007

2.016

1.623–3.669

0.003

  1. HR hazard ratio, CI confidence interval