Fig. 3: The membranal and cytoplasmic lnc-INSR associated with Treg distribution. | Cell Death & Disease

Fig. 3: The membranal and cytoplasmic lnc-INSR associated with Treg distribution.

From: Bone marrow infiltrated Lnc-INSR induced suppressive immune microenvironment in pediatric acute lymphoblastic leukemia

Fig. 3

a The percentage of Treg in the infiltrated CD4 (+) T cell was detected by flow cytometry in 96 paired clinical samples CD4, CD25, and Foxp3 was used as biomarker for Treg. b Pearson correlation analysis between the Treg distribution and the expression of lnc-INSR. c The subcellular location of lnc-INSR was examined by FISH in T cells extracted from T-ALL children. INSR location was detected by IF. ER stained with red was applied as membrane marker. DAPI was used for control stain. INSR was stained with green, lnc-INSR was yellow

Back to article page