Fig. 4: The effect of miR-10a overexpression on cancer GC by using an orthotopic model.
From: MicroRNA-10a promotes granulosa cells tumor development via PTEN-AKT/Wnt regulatory axis
a Stable miR-10a OE in KGN cells was established by GFP sorting. b The tumor burden of KGN cells OE miR-10a was larger than that of control KGN cells (n = 5). c H&E staining for histological analysis of miR-10a OE KGN cells and NC KGN cells injected ovaries (triangles indicated some normal follicles still could be found in NC KGN cells injected ovaries). d The effects of miR-10a on proliferation marker PCNA and two Wnt components (GSK-3β and β-Catenin) in control KGN cells and miR-10a OE KGN cells-formed tumor. e The effect of miR-10a on nuclear β-Catenin in control KGN cells and miR-10a OE KGN cells-formed tumor. OE overexpression
