Table 2 Univariate and multivariate Cox regression analyses in colon cancer patients

From: HCRP-1 regulates EGFR–AKT–BIM-mediated anoikis resistance and serves as a prognostic marker in human colon cancer

Variable

HCRP-1 staining

Univariate

Multivariate

HR (95% CI)

P-value

HR (95% CI)

P-value

HCRP-1

 

<0.001*

 

<0.001*

  Negative

1.000 (reference)

 

1.000 (reference)

 

  Positive

0.219 (0.122–0.392)

 

0.237 (0.130–0.431)

 

Age (years)

 

0.098

  

  ≤67

1.000 (reference)

   

  >67

1.617 (0.916–2.854)

   

Gender

 

0.351

  

  Male

1.000 (reference)

   

  Female

0.763 (0.432–1.347)

   

Tumor size (cm)

 

0.709

  

  ≤5

1.000 (reference)

   

  >5

1.110 (0.642–1.918)

   

pT status

 

0.538

  

  pT2 + pT3

1.000 (reference)

   

  pT4

1.197 (0.676–2.119)

   

pN status

 

0.082

  

  pN0

1.000 (reference)

   

  pN1 + pN2

1.627 (0.941–2.813)

   

pM status

 

0.001*

 

0.054

  pM0

1.000 (reference)

 

1.000 (reference)

 

  pM1

5.142 (1.984–13.326)

 

2.592 (0.985–6.820)

 

TNM stage

 

0.052

  

  I + II

1.000 (reference)

   

  III + IV

1.725 (0.994–2.992)

   

Grade

 

0.446

  

  G1

1.000 (reference)

   

  G2 + G3

1.392 (0.594–3.261)

   
  1. HR hazard ratio, CI confidence interval
  2. *P-value  <0.05 shows statistical significance
Back to article page