Fig. 6: Mechanism of the H19/miR-29b-3p/MCL-1 regulation axis in promoting BTZ resistance in MM cells.

The high expression of H19 in MM can be used as a ceRNA to inhibit miR-29b-3p, thus attenuating the inhibitory effect of miR-29b-3p on the target protein MCL-1, which causes a large number of translations of MCL-1 to inhibit apoptosis and induce BTZ resistance