Fig. 2: Plasma treatment increased toxicity in tumor spheroids pretreated with cytotoxic agents. | Cell Death & Disease

Fig. 2: Plasma treatment increased toxicity in tumor spheroids pretreated with cytotoxic agents.

From: Combination of chemotherapy and physical plasma elicits melanoma cell death via upregulation of SLC22A16

Fig. 2

a SK-MEL 28 tumor spheroids were treated with 1 µM of indicated drugs for 24 h, followed by exposure to cold physical plasma and further incubation for 24 h before staining with Hoechst and sytox orange. b Quantification of tumor cell toxicity. Results are shown as mean ± SEM. **p < 0.01; ***p < 0.001. Significance determined by one-way ANOVA with Tukey post-test for multiple comparisons. Scale bar: 250 µm

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