Fig. 3: Chemotherapeutics and plasma treatment increased DNA damage response in melanoma cells. | Cell Death & Disease

Fig. 3: Chemotherapeutics and plasma treatment increased DNA damage response in melanoma cells.

From: Combination of chemotherapy and physical plasma elicits melanoma cell death via upregulation of SLC22A16

Fig. 3

SK-MEL 28 cells were exposed to combination treatment as indicated. Cells were fixed and stained with anti γ-H2AX (a) or anti pATM (b) antibodies for immunofluorescence, and nuclear fluorescence was quantified. c Representative images and quantification of micronuclei in SK-MEL 28 cells following combination treatment. Data are represented as mean ± SEM derived from three independent experiments. **p < 0.01; ****p < 0.0001. Significance determined by one-way ANOVA with Tukey post-test for multiple comparisons. Scale bar: 100 µm

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