Fig. 1: SIRT2 was overexpressed and related to poor prognosis in CRC. | Cell Death & Disease

Fig. 1: SIRT2 was overexpressed and related to poor prognosis in CRC.

From: Inhibition of SIRT2 limits tumour angiogenesis via inactivation of the STAT3/VEGFA signalling pathway

Fig. 1

a, b Analysis of SIRT2 levels in CRC tumour tissues compared to those in normal samples using Oncomine databases. *P < 0.05. c Analysis of SIRT2 protein levels in 12 paired CRC samples and adjacent normal tissues. d Quantification of the protein levels of SIRT2 in 12 paired CRC samples and adjacent normal tissues. N: normal, T: tumour, **P < 0.01. e Immunohistochemistry (IHC) staining of SIRT2 in CRC tumour tissues and adjacent normal tissues (n = 46). f Vertical scatter plots showing that the IHC score for SIRT2 in the CRC tissue was significantly higher than that in the adjacent normal tissue. ***P < 0.001. g SIRT2 levels in different TNM stage patients from GSE24551. *P < 0.05. h Kaplan–Meier analysis showing that the high expression of SIRT2 is related to poor prognosis in CRC from GSE24551. P = 0.0225

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