Fig. 4: CDX2 inhibits the proliferation of colon cancer cells by arresting the cell cycle transition from G0/G1 to S phase. | Cell Death & Disease

Fig. 4: CDX2 inhibits the proliferation of colon cancer cells by arresting the cell cycle transition from G0/G1 to S phase.

From: CDX2 inhibits the proliferation and tumor formation of colon cancer cells by suppressing Wnt/β-catenin signaling via transactivation of GSK-3β and Axin2 expression

Fig. 4

a Fluorescence-activated cell sorting (FACS) analysis of the cell cycle distribution was shown for CDX2-knockdown HT-29 cells. b Comparison of the cell cycle distribution of CDX2-knockdown HT-29 cells. c The FACS analysis of cell cycle distribution was shown for CDX2-overexpressing HT-29 cells. d Comparison of the cell cycle distribution of CDX2-overexpressing HT-29 cells. e The FACS analysis of the cell cycle distribution was shown for CDX2-knockdown Caco-2 cells. f Comparison of the cell cycle distribution of CDX2-knockdown Caco-2 cells. g The FACS analysis of the cell cycle distribution was shown for CDX2-overexpressing Caco-2 cells. h Comparison of the cell cycle distribution of CDX2-overexpressing Caco-2 cells. All data are the mean ± SD of three independent experiments. *P < 0.05

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