Fig. 6: CDX2 regulates the expression of GSK-3β and Axin2 in colon cancer cells. | Cell Death & Disease

Fig. 6: CDX2 regulates the expression of GSK-3β and Axin2 in colon cancer cells.

From: CDX2 inhibits the proliferation and tumor formation of colon cancer cells by suppressing Wnt/β-catenin signaling via transactivation of GSK-3β and Axin2 expression

Fig. 6

a, b The mRNA expression of APC, Axin2, and GSK-3β in CDX2-knockdown (a) and CDX2-overexpressing (b) HT-29 cells. c, d The mRNA expression of APC, Axin2, and GSK-3β in CDX2-knockdown (c) and CDX2-overexpressing (d) Caco-2 cells. e, f Western blot bands of APC, Axin2, and GSK-3β in CDX2-knockdown and CDX2-overexpressing HT-29 (e) and Caco-2 (f) cells. All data are the mean ± SD of three independent experiments. *P < 0.05

Back to article page