Fig. 9: LAMB3 promotes pancreatic cancer cell invasion and migration in vivo. | Cell Death & Disease

Fig. 9: LAMB3 promotes pancreatic cancer cell invasion and migration in vivo.

From: LAMB3 mediates apoptotic, proliferative, invasive, and metastatic behaviors in pancreatic cancer by regulating the PI3K/Akt signaling pathway

Fig. 9

a Representative H&E-stained images of liver tissue sections from BALB/c nude mice injected with PANC-1 or MIA PaCa-2 LAMB3U, LAMB3D, or NC cells (scale bars: 100 μm (left) and 50 μm (right)). b LAMB3 expression was determined in representative metastatic liver tumor foci sections from the xenografts using IHC (scale bars: 100, 50, and 20 μm from left to right). c The number of metastatic liver nodules in each group was observed (n = 5, **P < 0.01, ***P < 0.001). d Kaplan–Meier analysis of the overall survival rate for each group (n = 5, *P < 0.05, **P < 0.01, ***P < 0.001)

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