Fig. 7: The effects of EZH2 on CRC cells. | Cell Death & Disease

Fig. 7: The effects of EZH2 on CRC cells.

From: Long non-coding RNA ZNFX1-AS1 promotes the tumor progression and metastasis of colorectal cancer by acting as a competing endogenous RNA of miR-144 to regulate EZH2 expression

Fig. 7

a The expression of EZH2 in CRC tissues and adjacent normal tissues by IHC. b Relative expression of EZH2 mRNA in CRC cell lines (SW620, SW480, HT-29, DLD-1, RKO, LOVO) and immortalized colon epithelial cell line CCD-112CoN (*P < 0.05). c Relative expression of EZH2 mRNA in CRC tissues and adjacent normal tissues (*P < 0.05). d The mRNA level of EZH2 in SW620 and LOVO cells as measured by Real-time PCR after knockdown of EZH2. e The cell viabilities of SW620 and LOVO cells were measured by CCK-8 assays after transfected with si-EZH2 or control siRNA (*P < 0.05). f The colony formation capacities of SW620 and LOVO cells after transfected with si-EZH2 or control siRNA (*P < 0.05). g The invasion abilities of SW620 and LOVO cells after transfected with si-EZH2 or control siRNA (*P < 0.05). h The cell viabilities of SW620 and LOVO cells were measured by CCK-8 assays after transfected with si-EZH2, miR-144 inhibitor or both (*P < 0.05). i The invasion abilities of SW620 and LOVO cells after transfected with si-EZH2 or control siRNA (*P < 0.05)

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